Department
Psychiatry & Psychology
PTSD, Depression, Anxiety
0 FDA-approved
2 research
HBOT Applications
Investigational / Preclinical Level B
Post-Traumatic Stress Disorder (PTSD)
Clinical trials demonstrate HBOT improves brain microstructure functionality and alleviates PTSD symptoms in veterans with treatment-resistant PTSD. Significant improvements in PTSD checklist scores.
Protocol
Pressure
1.5 – 2.0 ATA
Duration
60 – 90 min
Sessions
40 – 60
Frequency
Once daily, 5×/week
Evidence basis: Level B Evidence (RCT)
References: 20
Investigational / Preclinical Level C
Treatment-Resistant Depression
Emerging research investigates HBOT for treatment-resistant depression through neuroplasticity enhancement, BDNF upregulation, and reduction of neuroinflammation.
Protocol
Pressure
1.5 – 2.0 ATA
Duration
60 – 90 min
Sessions
20 – 40
Frequency
Once daily, 5×/week
Evidence basis: Investigational
References: 8