Longevity application

Collagen Production & Skin Health

3×

Increase in collagen III formation

HBOT stimulates collagen III formation and increases overall collagen production through growth factor upregulation, supporting skin elasticity, joint health, and connective tissue integrity.

Mechanism

Hyperoxia upregulates VEGF, PDGF, and FGF, promoting fibroblast proliferation and collagen synthesis. HBOT also enhances hydroxylation of proline and lysine residues, critical steps in collagen cross-linking and tissue strength.

Treatment protocol

Protocol

Pressure

2.0 – 2.4 ATA

Duration

90 min

Sessions

20 – 40

Frequency

Once daily, 5×/week

Evidence basis: Clinical Research

Key References:

11

See full citations on the references page.