Department

Geriatric Assessment

Physical Performance, Cognitive Aging

0 FDA-approved 3 research

HBOT Applications

Investigational / Preclinical Level A (RCT)

Physical Performance Enhancement

Randomized controlled trial demonstrated HBOT improves maximal physical performance and cardiac perfusion in sedentary older adults, enhancing exercise capacity and cardiovascular function.

Protocol

Pressure

2.0 ATA

Duration

90 min

Sessions

40 – 60

Frequency

Once daily, 5×/week

Evidence basis: RCT (Doenyas-Barak et al., 2024)

References: 21
Investigational / Preclinical Level B

Cognitive Decline Prevention

HBOT reverses age-related cerebral hypoperfusion and promotes angiogenesis in brain tissue, potentially preventing or slowing cognitive decline in aging populations.

Protocol

Pressure

2.0 ATA

Duration

90 min

Sessions

60

Frequency

Once daily, 5×/week

Evidence basis: RCT (Hadanny et al., 2020)

References: 4 5
Investigational / Preclinical Level B

Cellular Aging Reversal

First human evidence of telomere lengthening (>20%) and senescent cell clearance through 60 HBOT sessions in healthy older adults, representing a novel anti-aging intervention.

Protocol

Pressure

2.0 ATA

Duration

90 min

Sessions

60

Frequency

Once daily, 5×/week

Evidence basis: Hadanny et al., 2020 (RCT)

References: 3