HBOT activates telomerase, induces senolytic effects, mobilizes stem cells, and enhances antioxidant defense through the hyperoxic-hypoxic paradox.

Detailed mechanism

Repeated HBOT sessions activate telomerase (increasing telomere length by >20%), selectively eliminate senescent cells, mobilize bone marrow stem cells via NOS activation, and upregulate endogenous antioxidants (SOD, catalase, glutathione peroxidase) through hormetic stress responses.

Key References:

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